Extreme malice; violent hatred; malignity; malice irritated or enraged; active malignity; angry hatred. With all thy despite against the land of israel. Ezekiel 25:6.

Defiance with contempt, or contempt of opposition. He will rise to fame in despite of his enemies.

An act of malice or contempt; as a despite to the Most High.

To vex; to offend; to tease.