Properly, to strive, or to make efforts with a twisting or with contortions of the body. Hence,

To use great efforts; to labor hard; to strive; to contend; as, to struggle to save life; to struggle with the waves; to struggle against the stream; to struggle with adversity.

To labor in pain or anguish; to be in agony; to labor in any kind of difficulty or distress. Tis wisdom to beware, and better shun the bait than struggle in the snare.

Great labor; forcible effort to obtain an object, or to avoid an evil; properly, a violent effort with contortions of the body.

Contest; contention; strife. An honest man might look upon the struggle’ with indifference.

Agony; contortions of extreme distress.