To injure the substance or qualities of a thing, so as to impair or spoil its use and value. Thus we say, luxury vitiates the humors of the body; evil examples vitiate the morals of youth; language is vitiated by foreign idioms. This undistinguishing complaisance will vitiate the taste of readers.

To render defective; to destroy; as the validity or binding force of an instrument or transaction. Any undue influence exerted on a jury vitiates their verdict. Fraud vitiates a contract.